Alan H Jobe Selected Research

Betamethasone (Celestone)

1/2022	Betamethasone phosphate reduces the efficacy of antenatal steroid therapy and is associated with lower birthweights when administered to pregnant sheep in combination with betamethasone acetate.
1/2018	Extremely preterm fetal sheep lung responses to antenatal steroids and inflammation.
1/2018	The efficacy of antenatal steroid therapy is dependent on the duration of low-concentration fetal exposure: evidence from a sheep model of pregnancy.
10/2016	Antenatal corticosteroids beyond 34 weeks gestation: What do we do now?
1/2016	The placental membrane microbiome is altered among subjects with spontaneous preterm birth with and without chorioamnionitis.
12/2013	Modulation of lipopolysaccharide-induced chorioamnionitis in fetal sheep by maternal betamethasone.
1/2013	Effects of intra-amniotic lipopolysaccharide and maternal betamethasone on brain inflammation in fetal sheep.
2/2012	Intra-amniotic LPS and antenatal betamethasone: inflammation and maturation in preterm lamb lungs.
12/2009	Antenatal and postnatal corticosteroid and resuscitation induced lung injury in preterm sheep.
1/2009	Ureaplasma colonization of amniotic fluid and efficacy of antenatal corticosteroids for preterm lung maturation in sheep.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Alan H Jobe Research Topics

Disease

70	Inflammation (Inflammations) 01/2022 - 02/2002
54	Chorioamnionitis 01/2022 - 01/2002
36	Pneumonia (Pneumonitis) 01/2021 - 02/2002
28	Lung Injury 01/2022 - 06/2002
24	Bronchopulmonary Dysplasia 06/2021 - 03/2002
20	Premature Birth (Birth, Premature) 01/2021 - 05/2002
17	Infections 05/2020 - 10/2010
11	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2021 - 11/2002
8	Premature Obstetric Labor (Premature Labor) 01/2022 - 01/2002
6	Acute-Phase Reaction 01/2018 - 12/2009
4	Lung Diseases (Lung Disease) 01/2022 - 01/2010
3	Birth Weight (Birth Weights) 01/2022 - 01/2003
3	Fetal Weight 01/2021 - 11/2003
3	Hyperoxia 01/2020 - 12/2009
3	Brain Injuries (Brain Injury) 04/2018 - 04/2004
3	Perinatal Death 08/2017 - 04/2004
3	Ureaplasma Infections (Ureaplasma Infection) 01/2017 - 09/2010
3	Stillbirth 06/2016 - 12/2011
3	Acidosis 06/2010 - 05/2002
3	Body Weight (Weight, Body) 05/2010 - 03/2002
2	Pre-Eclampsia (Preeclampsia) 01/2021 - 05/2011
2	Respiratory Insufficiency (Respiratory Failure) 01/2021 - 11/2019
2	Hyaline Membrane Disease 01/2020 - 02/2015
2	Asphyxia (Suffocation) 08/2017 - 08/2015
2	Hypertrophy 01/2016 - 12/2004
2	Hypothermia 01/2009 - 10/2005
2	Vascular Remodeling 01/2007 - 12/2004
2	Fibrosis (Cirrhosis) 01/2007 - 12/2004
1	COVID-19 01/2021
1	Iron Deficiencies 01/2020

Drug/Important Bio-Agent (IBA)

31	CytokinesIBA 01/2022 - 03/2003
29	Surface-Active Agents (Surfactants)IBA 06/2021 - 03/2002
28	LipopolysaccharidesIBA 01/2022 - 08/2005
27	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2022 - 11/2003
23	EndotoxinsIBA 03/2011 - 02/2002
19	Betamethasone (Celestone)FDA Link 01/2022 - 01/2002
19	Messenger RNA (mRNA)IBA 01/2021 - 03/2003
13	Proteins (Proteins, Gene)FDA Link 09/2014 - 06/2002
12	SteroidsIBA 01/2022 - 04/2003
12	Interleukin-1 (Interleukin 1)IBA 01/2018 - 03/2002
9	Oxygen (Dioxygen)IBA 01/2021 - 12/2009
8	Budesonide (Pulmicort)FDA LinkGeneric 06/2021 - 11/2003
8	Interleukin-8 (Interleukin 8)IBA 01/2017 - 11/2003
8	GlucocorticoidsIBA 03/2013 - 01/2002
6	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2022 - 07/2003
5	InterleukinsIBA 01/2021 - 09/2014
5	Anti-Bacterial Agents (Antibiotics)IBA 08/2017 - 10/2010
4	LigandsIBA 01/2018 - 04/2009
4	LipidsIBA 01/2017 - 06/2002
4	AntigensIBA 01/2017 - 09/2010
4	Interleukin-6 (Interleukin 6)IBA 01/2016 - 04/2009
3	Saline SolutionIBA 01/2021 - 10/2002
3	ChemokinesIBA 01/2017 - 03/2003
3	Erythromycin (Erycette)FDA LinkGeneric 08/2014 - 10/2010
3	Interleukin-1alpha (Interleukin 1 alpha)IBA 09/2006 - 03/2002
3	acivicin (AT 125)IBA 01/2003 - 08/2002
2	RNA (Ribonucleic Acid)IBA 01/2022 - 01/2021
2	betamethasone sodium phosphate FDA LinkGeneric 01/2022 - 01/2018
2	IronIBA 01/2021 - 01/2020
2	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2021
2	gamma-sitosterol (beta-sitosterol)IBA 05/2020 - 04/2019
2	campesterolIBA 05/2020 - 04/2019
2	Phytosterols (Plant Sterols)IBA 05/2020 - 04/2019
2	Peroxidase (Myeloperoxidase)IBA 04/2019 - 05/2009
2	Virulence Factors (Pathogenicity Factors)IBA 01/2017 - 01/2012
2	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 01/2017 - 11/2016
2	CollagenIBA 01/2016 - 12/2004
2	Fluconazole (Zonal)FDA LinkGeneric 01/2016 - 06/2015
2	Oxidants (Oxidizing Agents)IBA 01/2015 - 03/2008
2	Acute-Phase Proteins (Acute-Phase Protein)IBA 09/2013 - 12/2005
2	Transforming Growth Factors (Transforming Growth Factor)IBA 03/2013 - 01/2007
2	Hydrocortisone (Cortisol)FDA LinkGeneric 02/2011 - 01/2003
2	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2011 - 04/2009
2	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 05/2009 - 11/2005
2	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 04/2009 - 03/2003
2	AT 130IBA 05/2005 - 03/2004
1	Acetates (Acetic Acid Esters)FDA Link 01/2022
1	betamethasone acetate FDA LinkGeneric 01/2022
1	Proto-Oncogene Proteins c-etsIBA 02/2021
1	poractant alfa (Curosurf)FDA Link 01/2021
1	2-methylpentaneIBA 01/2021
1	Volatile Organic CompoundsIBA 01/2021
1	Interferon Type IIBA 01/2021
1	Granulocyte-Macrophage Colony-Stimulating Factor Receptors (GM-CSF Receptor)IBA 01/2021
1	101.10 peptideIBA 01/2021
1	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 01/2021
1	CyclodextrinsIBA 05/2020
1	Transcription Factors (Transcription Factor)IBA 01/2020
1	HepcidinsIBA 01/2020

Therapy/Procedure

26	Artificial Respiration (Mechanical Ventilation) 01/2021 - 02/2002
11	Therapeutics 01/2022 - 01/2002
8	Resuscitation 08/2017 - 10/2005
2	Prenatal Care (Care, Prenatal) 12/2011 - 05/2011
2	Continuous Positive Airway Pressure 01/2009 - 09/2002
2	Injections 12/2007 - 01/2002
2	Aftercare (After-Treatment) 04/2003 - 10/2002
1	Off-Label Use 01/2021
1	Bronchoscopes 01/2021
1	Catheters 01/2021
1	Critical Care (Surgical Intensive Care) 01/2020